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Motor Neuron Diseases Information Page

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What are Motor Neuron Diseases?
Is there any treatment?
What is the prognosis?

What are Motor Neuron Diseases?
Motor neuron diseases (MNDs) are progressive, degenerative disorders that affect nerves in the upper or lower parts of the body. Some of the diseases are inherited, while others may be acquired. Common MNDs include amyotrophic lateral sclerosis (ALS), progressive muscular atrophy, and postpolio syndrome. usually, MNDs strike in middle age. Symptoms may include difficulty swallowing, limb weakness, slurred speech, impaired gait, facial weakness, and muscle cramps. Respiration may be affected in the later stages of these diseases. The cause(s) of most MNDs are not known, but environmental, toxic, viral, or genetic factors may be implicated.

Is there any treatment?
There is no cure, nor standard treatment, for MNDs. Treatment is symptomatic and supportive. Physical therapy, drug therapy, and assistive devices may help some individuals.

What is the prognosis?
The prognosis for individuals with these disorders varies depending on the type of MND. Some types, such as ALS, are fatal.

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